Nicky Henderson expects to know by Thursday evening whether his horses are over whatever was ailing them during the Cheltenham Festival, with Sir Gino and Shishkin all set for Aintree.

Henderson endured a miserable week in the Cotswolds and after racing on Wednesday of that week decided discretion was the better part of valour, pulling out all of his high-profile runners.

“Rather like before Cheltenham we’ve kept testing them and just like then, everything is fine – that’s the only worry really. It keeps telling us everything is fine,” said Henderson.

“The horses seem really well in themselves, the last work has all been done, they seem bright and perky and we’re looking forward to it.

“We’re going to know our fate pretty quickly. By Thursday night it will either be happening or it won’t be happening. Obviously we go with a fair amount of trepidation, but things seemed to have improved dramatically from the perspective of their work and everything at home.

“We’ve hardly run anything, but the two reasons we haven’t run anything, for instance at Hereford today I couldn’t make an entry on the card – I couldn’t find a horse who was qualified to run in any race, and of course the ground is desperate, so we’ll start at Aintree.”

After a quiet 10 days the Seven Barrows handler has been building them back up to peak fitness and Sir Gino, who had been odds-on for the Triumph Hurdle, will be first to test the water in the Boodles Anniversary 4-Y-O Juvenile Hurdle.

“He was a horse that I honestly couldn’t find anything wrong with him, but we’d lost all confidence and I couldn’t face running a young horse like him,” Henderson told Sky Sports Racing.

“We’ve made no bones about it, we think he’s seriously good and I just couldn’t risk him. Joe Donnelly was wonderful because we had to take Sir Gino, Shishkin and Shanagh Bob out, all his, but there was no point in running them after the first two days.

“I trust in this fellow and he’s going to go out there carrying the Seven Barrows flag and I’m sure everyone is going to watch him like a hawk – I hope for all the right reasons.

“He won at Auteuil and as everybody knows, if you can handle that you can handle most things, and it was pretty soft on Trials day (at Cheltenham).”

Shishkin will then get his chance to shine in the Aintree Bowl having missed the Gold Cup.

“The last week seems to have been great, Nico (de Boinville) rode him in his last piece of work on Saturday and said he felt fantastic and he’s looked up for it all this week.

“I just think everything has gone right, but he’s had a funny old year. He didn’t start, then he threw away the King George and then he won the Denman. Whatever anybody’s opinion of the King George doesn’t matter, he was still running a great race. The Denman was more than an ideal preparation for the Gold Cup, but here we are in the same place so hopefully all systems go.”

Henderson also runs the mares Luccia and Marie’s Rock in the William Hill Aintree Hurdle.

He said: “Luccia was the one bright light at Cheltenham. The Champion Hurdle had fallen apart as far as we were concerned without Constitution Hill, but Luccia ran a fantastic race when she was a very close third.

“The only thing here is we are going up half a mile. We haven’t thought about it a lot and always felt she wouldn’t stay, but one day you have to try and if she does stay from next season’s point of view it gives her so many more options. The alternative was to wait for Punchestown and walk into Lossiemouth.

“Marie’s Rock is between here and the three-miler, but in this sort of ground two and a half will be plenty for her. She’s got stamina and goes in the soft, but it’s a very tough race.”